Malegra contains sildenafil citrate, which is a medication used to treat erectile dysfunction. Grapefruit and grapefruit juice contain compounds that can interfere with the metabolism of certain medications, including sildenafil.
Grapefruit contains substances called furanocoumarins, which inhibit the activity of an enzyme called CYP3A4 in the intestines. This enzyme is involved in the breakdown of many medications, including sildenafil. When CYP3A4 is inhibited, it can lead to higher levels of sildenafil in the bloodstream, increasing the risk of side effects.
Consuming grapefruit or grapefruit juice while taking Malegra can potentially increase the concentration of sildenafil in your blood, leading to a higher risk of side effects such as headache, dizziness, flushing, and low blood pressure.
To avoid potential interactions, it's essential to follow your healthcare provider's recommendations and avoid consuming grapefruit or grapefruit juice while taking Malegra or any medication containing sildenafil. If you have any questions or concerns about dietary restrictions while taking Malegra, I recommend discussing them with your healthcare provider for personalized advice.
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