Vriligy 60 mg is a medication primarily used for the treatment of premature ejaculation (PE). Here are its main features:
Active Ingredient: Vriligy 60 mg contains dapoxetine hydrochloride, which is a selective serotonin reuptake inhibitor (SSRI) specifically developed for the treatment of PE.
Mechanism of Action: Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the postsynaptic cleft, and delaying ejaculation reflex, thereby improving control over ejaculation.
Indication: It is indicated for men aged 18 to 64 years who experience recurrent or persistent PE, characterized by ejaculation that occurs with minimal sexual stimulation before, upon, or shortly after penetration, and before the individual wishes.
Dosage: The standard dosage is 60 mg taken orally as needed, approximately 1 to 3 hours before anticipated sexual activity. It should be taken with a full glass of water to facilitate absorption.
Effectiveness: Clinical trials have shown that Vriligy 60 mg significantly increases the time to ejaculation and improves control over ejaculation compared to placebo.
Safety Profile: It has a generally favorable safety profile when used as directed. Common side effects may include nausea, headache, dizziness, insomnia, and diarrhea. Serious adverse effects are rare but can include serotonin syndrome and orthostatic hypotension.
Contraindications: Similar to other medications of its class, Vriligy 60 mg is contraindicated in patients with hypersensitivity to dapoxetine or any inactive ingredients, severe hepatic impairment, severe renal impairment, and concomitant use with monoamine oxidase inhibitors (MAOIs) or thioridazine.
Precautions: It is important to use Vriligy 60 mg cautiously in patients with a history of orthostatic hypotension, mania/hypomania, or seizures, as well as in those using medications that may lower the seizure threshold or affect blood pressure.
Usage Guidelines: Patients should be instructed to take Vriligy 60 mg only when needed and not more than once daily. It should not be used continuously on a daily basis.
As with any medication, it's essential to consult with a healthcare provider before starting Vriligy 60 mg to discuss individual health factors, potential interactions with other medications, and to ensure safe and effective use for the management of premature ejaculation.
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