Vidalista Black 80 mg (which contains Tadalafil 80 mg) and potentially cause side effects or affect how the medication works. This interaction is mainly due to the presence of furanocoumarins in grapefruit, which can inhibit the activity of an enzyme called CYP3A4 in the liver. How the Interaction Works: CYP3A4 Inhibition: Tadalafil (the active ingredient in Vidalista) is metabolized by the CYP3A4 enzyme in the liver. Grapefruit can reduce the activity of this enzyme, leading to higher levels of Tadalafil in the bloodstream than expected. Increased Risk of Side Effects: Because the medication remains in the body for a longer period, this can increase the risk of side effects, including: Headaches Flushing Dizziness or lightheadedness Low blood pressure Indigestion Back pain Prolonged erections (priapism), which is a serious side effect requiring immediate medical attention. What You Should Do: Avoid Grapefruit: It’s generally recommended to avoid grapefruit and grapefruit juice while taking Vidalista Black 80 mg or any medication containing Tadalafil, as the interaction could enhance the side effects and potentially cause harm. Consult Your Doctor: If you regularly consume grapefruit or grapefruit juice and have been prescribed Vidalista Black 80 mg, discuss this with your healthcare provider. They may recommend alternatives or advise how to manage the interaction.
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