EMSA is a lab method that helps researchers spot and study how proteins interact with nucleic acids. Basically, you take a labeled nucleic acid probe, mix it with a protein sample, and then run it through a non-denaturing gel. If the protein binds to the probe, the combo moves slower through the gel than the free probe, making a clear band shift. You can see this shift using techniques like autoradiography, fluorescence, or chemiluminescence. This movement tells you there's a protein-nucleic acid interaction going on, offering clues about how specific and strong the binding is.
Profacgen offers a handy Electrophoretic Mobility Shift Assay (EMSA) service, ideal for exploring those complex protein-nucleotide interactions. It's super useful if you're researching gene regulation, transcription factor binding, or the details of DNA repair and RNA processing. They handle everything from prepping your samples and labeling nucleotides to running the electrophoresis and breaking down the data. So, you can count on them for top-notch results that'll really drive your research forward.
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